General
Von Willebrand disease is the most common congenital bleeding disorder. The cause is a genetic mutation that results in reduced quantity or impaired function of the von Willebrand factor, which plays a crucial role in the blood clotting process. Its prevalence in the population is estimated to be around 1%. Bleeding manifestations vary in intensity, generally mild, and most affected individuals do not seek medical attention. The disease is named after the Finnish physician Erik von Willebrand, who first described the hereditary bleeding disorder in 1924 in families on the Åland Islands.
Treatment:
Treatment is usually not necessary. Administration of von Willebrand factor as a concentrated injectable form is possible, though expensive, and is mainly used temporarily before surgical procedures. Desmopressin may also be used to increase factor levels. Preventing severe injuries is important, and high-risk activities such as adrenaline sports are not recommended.
- najrôznejšie krvácajúce prejavy
- ľahká tvorba hematómov (modrín)
- epistaxa (krvácanie z nosa) s možnosťou prieniku krvi do kanála spájajúceho nosnú dutinu s očami (canalis nasolacrimalis), to môže spôsobiť "ronenie krvavých sĺz"
- krvácanie z ďasien
- väčšie menštruačné krvácanie u žien
- silnejšie krvácanie pri pôrode
- skoré krvácanie pri poraneniach a operáciách
- krvácanie do tráviaceho traktu
- často tiež krv v stolici alebo krv v moči
- krvácanie do kĺbov a svalov u ťažkých foriem
To connect with other people with the same diagnosis in your area, please log in.
Login