General
Gilbert syndrome is the most common form of benign hyperbilirubinemia (a non‑serious increase in bilirubin levels in the blood). It is an inherited condition that affects 5–10% of the population and occurs more frequently in males. The syndrome is usually discovered incidentally during examinations of adolescents, most often between the ages of 15 and 20.
Treatment:
Therapy is not necessary; in fact, it is discussed that Gilbert syndrome may have a protective effect against atherosclerosis, especially of the coronary (heart) arteries. The prognosis is favorable.
- mild jaundice
- biochemistry: bilirubin in the blood up to 80 µmol/L intermittently (occasionally)
- worsening of the condition during infection, heavy physical strain, surgery, or fasting — during these periods the following may occur:
- feelings of nausea
- increased fatigue
- pressure under the right rib
- subicterus of the sclera (yellow discoloration of the whites of the eyes). Laboratory findings: aside from elevated total bilirubin, all other parameters are within normal limits.
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